Novel Unsteady State Method of Measuring Permeability Tested on Fabric Materials

The necessity of measuring permeability is encountered in number applications and some them have adequate measurement techniques available. However, the fields freeze drying, composite scaffolds, 3D printed materials, etc., sample materials unique shapes sizes, which disables use standardized equipment. Hence, a novel method was developed to determine material by analyzing high frequency unsteady state pressure acquired during permeation working fluid. also suitable for in-line measurements due rapid acquisition analysis. novel, hence comparison results permeabilities measured with standard device designed air fabric made. Air permeating fluid as well referential steady measurements. ranged from approximately 8 Da 50 analyzed five materials. comparative analysis yielded an encouraging linear fit R2 = 0.98 including only one each sample. In addition, presented capable detecting difference freeze-dried 5 wt% 12 aqueous mannitol solutions, exhibit different porosities after same process lyophilization. possibility determining pharmaceuticals essential lyophilization optimization.